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The Trump Presidency

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:04am
Originally posted by Isaac soloman Isaac soloman wrote:

As is usual pt, just causing mischief.

You and Redemption are pushing the using of powerful drugs with severe side effects without a prescription to treat a disease that it hasn't been tested on and I am the one being mischievous? 

You are being totally reckless and irresponsible.


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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:09am
Where did i say to take irresponsibly?
Cant imagine you could get it without a prescription.

Mischief making again pt.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Shammy Davis Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:09am
Originally posted by Passing Through Passing Through wrote:

Has it been cleared for treatment of COVID -19 ISAAC?
Yes. In the states, it is approved for off label use for COVID19. Parallel trials are continuing.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:14am
They have this thing called a black market Isaac, and it seems a lot of people are abusing the system to on-sell drugs.


New restrictions on prescribing hydroxychloroquine for COVID-19

24 March 2020

In recent days there has been considerable focus on the potential for hydroxychloroquine and the similar compound chloroquine (which is not marketed in Australia) to help in treating COVID-19.

Hydroxychloroquine is used for treatment of malaria and certain autoimmune diseases.

Recent reports of increased off-label prescribing of medicines containing hydroxychloroquine have raised concerns that this will create a potential shortage of this product in Australia.

Clinical trials are underway around the world examining their potential to treat COVID-19. However, these medicines pose well-known serious risks to patients including cardiac toxicity (potentially leading to sudden heart attacks), irreversible eye damage and severe depletion of blood sugar (potentially leading to coma).

Given the limited evidence for effect against COVID-19, as well as the risk of significant adverse effects, the TGA strongly discourages the use of hydroxychloroquine outside of its current indications at this time other than in a clinical trial setting or in a controlled environment in the treatment of severely ill patients in hospital.

To limit use of hydroxychloroquine to currently approved indications, there have been new restrictions placed on who can initiate therapy using it. Only certain types of specialists will be able to prescribe hydroxychloroquine to new patients (see information for health professionals below). General practitioners and other medical practitioners (e.g. hospital Resident Medical Officers (RMOS) and doctors in training) can continue to prescribe repeats for hydroxychloroquine to patients in line with the registered indications for patients in whom the medication was prescribed prior to 24 March 2020. From 24 March 2020, general practitioners and doctors in training can only prescribe these medicines for continued treatment of patients where initial treatment has been authorised by one of the specialists.

https://www.tga.gov.au/alert/new-restrictions-prescribing-hydroxychloroquine-covid-19

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:19am
I had better get my LEGIT prescriptions filled before the likes of you hit the black market to buy up and make it HARD for genuine users, like me to get it.
Another thing pt, the stuff on the black market can be dangerous i believe.
Made from questionable substances, sourced in CHINA, made in CHINA.

Be careful pt....
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:19am
Why wouldn't you have a crack at this stuff eh Isaac? Nothing to lose says Donald. That old bloke and his missus beg to differ.

Hydroxychloroquine

Hydroxychloroquine is indicated for rheumatoid arthritis; mild systemic and discoid lupus erythematosus; the suppression and treatment of malaria. Hydroxychloroquine has a long half-life of >30 days.

Contraindications:

  • Children <6 years
  • Pre-existing maculopathy
  • Known hypersensitivity to hydroxychloroquine/chloroquine
  • Long-term therapy in children.

Adverse effects:

  • Cardiac toxicity including fatal cardiomyopathy
  • Severe hypoglycaemia (low blood sugar) with loss of consciousness
  • QT interval prolongation
  • Blurred vision, irreversible retinal damage
  • Skin reactions including rash/itch
  • GI disturbances including nausea/vomiting/abdominal cramps/diarrhoea
  • Muscle weakness
  • Headache
  • Alopecia
  • Blood dyscrasias, monitoring required for long-term treatment.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:22am
ooh i feel a little bit special, legitimately contributing to this EXPERIMENT! for coronavirus, that is.
My problem is not an experiment using plaquenil.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote maccamax Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:26am
Almost ALL drugs have some side effects .

We shouldn't jump to conclusions about anything.     . These Drugs that were used in previous epidemics/pandemics , would be undergoing massive research to find the best suitable , for the present outbreak.

The World Fcked up in not being better prepared for the inevitable outbreaks of these Virus attacks ( every decade or so )

( I always understood the word VIRUS meant NO CURE AVAILABLE...)
Antibiotics cure Bacteria infections
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:26am

Treating Lupus with Anti-Malarial Drugs

  • Hydroxychloroquine (Plaquenil)
  • Chloroquine (Aralen)
  • Quinacrine (Atabrine)

    What are anti-malarial drugs, and why are they used to treat lupus?

    Hydroxychloroquine (Plaquenil), chloroquine (Aralen), and quinacrine (Atabrine) are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Specifically, anti-malarial medications have shown to improve muscle and joint pain, skin rashes, pericarditis (inflammation of the lining of the heart), pleuritis (inflammation of the lining of the lung), and other lupus symptoms such as fatigue and fever. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system (your brain and spinal cord) and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of anti-malarials as a sort of “lupus life insurance.”

    Studies have shown lupus patients on anti-malarials actually live longer than those who are not, and these medications are usually prescribed when someone is first diagnosed with the disease. Anti-malarials are particularly useful in treating discoid lupus, subacute cutaneous lupus, and mouth sores associated with lupus; they are also effective in treating rheumatoid arthritis and Sjogren’s syndrome. However, anti-malarials are not a sufficient treatment for more severe lupus symptoms such as kidney disease and nervous system or blood vessel involvement. When lupus spreads to these organs, immunosuppressive medications are usually added to help minimize irreversible injury.

    What anti-malarial drugs are commonly prescribed for lupus?

    Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine (Plaquenil) is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine (Aralen) has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Quinacrine (Atabrine) is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the patient does not respond to Plaquenil alone. Quinacrine tablets are no longer manufactured and can only be obtained through a compounding pharmacist. Your doctor will advise you on how to obtain quinacrine if this becomes your advised method of treatment.

    How do anti-malarial drugs control lupus symptoms?

    Anti-malarial medications help to control lupus in several ways by modulating the immune system without predisposing you to infection. Anti-malarials can protect against UV light and sometimes even improve skin lesions that do not respond to treatment with topical therapy (ointments). Anti-malarial medications may prevent activation of plasmacytoid dendritic cells, a component of the immune system that is responsible for making interferon.

    Can anti-malarial drugs be taken with other lupus medications?

    Yes, anti-malarials can be taken with other lupus medications, including corticosteroids (e.g., prednisone), immunosuppressives, cytotoxic drugs, and NSAIDs. Anti-malarial drugs may be given in combination with prednisone to reduce the amount of steroid needed to control lupus symptoms and thus to alleviate some of the side effects of the steroid. In addition, since it usually takes about 1-3 months for your anti-malarial medications to fully take effect, you may be given a steroid medication to act as a bridging medication and alleviate your symptoms during this interim.

    Can anti-malarial drugs be taken during pregnancy?

    Anti-malarials are safe to use during pregnancy, but you should speak to your doctor if you are pregnant or may become pregnant to decide the course of treatment that will be best for you. No fetal abnormalities are known to have occurred from taking hydroxychloroquine, and physicians at several major universities have used anti-malarial drugs for years to treat pregnant women with lupus without negative side effects on the fetus.

    What should I keep in mind when taking anti-malarial drugs?

    Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine (Aralen). With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Follow-up exams every 6 months (or, annually at the very least) are also advised. You can also monitor yourself between visits with a special grid called an Amsler grid, which can be obtained through your ophthalmologist.

    If your ophthalmologist does find some Plaquenil deposits, s/he will simply request that you stop taking the medication, and you may follow up with your rheumatologist about another advised method of treatment. Unfortunately, retinal damage caused by Aralen may be irreversible, but this medication is rarely prescribed anymore for lupus.

    Do not smoke while taking anti-malarial medications, since smoking actually reduces the benefits of these drugs. In fact, people with lupus should not smoke at all due to their increased risk of cardiovascular disease.

    You should always take your anti-malarial medications with food to prevent stomach upset. If a stomachache does occur, it is usually temporary. However, if you experience stomach upset while taking generic hydroxychloroquine, ask your doctor about trying name-brand Plaquenil instead. While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation. This sort of upset usually does not occur with commercial Plaquenil. Your doctor can ensure that you receive this version of the medication by writing “do not substitute” on your script.

    Lastly, remember that even though you may feel the benefits of anti-malarial therapy after about a month of treatment, it may take up to three months for the full benefits of the drug to manifest. If you experience any serious adverse effects, notify your doctor.

    Can I stop taking anti-malarials suddenly?

    Long-term anti-malarial use is normally safe. However, if you stop taking your anti-malarial drugs, you may experience a lupus flare.

    Potential added benefits of anti-malarial drugs

    Anti-malarial drugs may have additional health benefits for some people. Potential benefits include greater protection from UV light and lower cholesterol and blood glucose levels. These benefits may be especially helpful for people taking steroids. In addition, individuals with antiphospholipid antibodies, such as the lupus anticoagulant and anticardiolipin antibodies, may experience a decreased likelihood of blood clots.

    What are the possible side effects of anti-malarial drugs?

    Most people (about 90%) who take anti-malarial medications experience no side effects. If side effects do occur, they are usually minor and last only for a short period of time.

    Potential side effects of anti-malarial drugs include:

    • Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone.
    • Dry skin
    • Loss of appetite
    • Abdominal bloating
    • Upset stomach
    • Stomach cramps
    • Retinal damage – There is a small chance that retinal damage will occur while taking hydroxychloroquine (Plaquenil) or chloroquine (Aralen). For this reason, you should see your ophthalmologist at least once per year so that she/he may check for retinal deposits. Retinal damage caused by hydroxychloroquine is generally reversible, but damage caused by chloroquine may not be. More information on this effect can be found above.
    • Less common side effects:
      • Headaches
      • Muscle aches
      • Weakness
      • Nervousness, irritability, dizziness (although these effects are uncommon)
      • Major neurological side effects: confusion, seizures – These are quite rare, but if you experience them, alert your doctor immediately.
      • Exacerbation of psoriasis – If you have psoriasis, Plaquenil may make your condition worse.     Talk to your doctor if you have this condition.https://www.hopkinslupus.org/lupus-treatment/lupus-medications/antimalarial-drugs/
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:27am
Whole picture pt not just a little bit.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:33am
Originally posted by maccamax maccamax wrote:

Almost ALL drugs have some side effects .

We shouldn't jump to conclusions about anything.     . These Drugs that were used in previous epidemics/pandemics , would be undergoing massive research to find the best suitable , for the present outbreak.

The World Fcked up in not being better prepared for the inevitable outbreaks of these Virus attacks ( every decade or so )

( I always understood the word VIRUS meant NO CURE AVAILABLE...)
Antibiotics cure Bacteria infections

This one is a mutated SARS virus whose actual name is SARS-coV-2 The resulting disease is called COVID-19.

The V in both names is for Virus. There is no ''cure'' but drugs like Remdesivir which was tried but failed as a cure for SARS is being considered a best hope because of it's common directive.

Literally hundreds of older drugs, alone and in combination are being extensively retested.  
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:35am
What's up Isaac, hijacking threads and trolling because nobody cares about your China hate thread?

#SAD
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:37am
*Ebola, not SARS failed drug maxie
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:44am
Originally posted by Passing Through Passing Through wrote:

What's up Isaac, hijacking threads and trolling because nobody cares about your China hate thread?

#SAD

trolling?
Giving genuine information pt...
China thread? Why "confine" info around China and its happenings to one thread?
China is all over the place nowadays. In more ways than one pt Tongue
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:46am
I am practicing strict social distancing so you can move out of my head any time you like...soonish.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:49am
I hope plaquinal can be the "cure"
but as macca said virus cant be "cured".

And all this turmoil because someone in WUHAN, CHINA decided to EAT? a pangolin.Image result for pangolin meme

AMAZINGImage result for pangolin meme
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 11:59am
Have i distracted you from trump goings on? 
You actually learned something today .LOL
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 12:01pm
Nothing I didn't already know.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 12:02pm
or suspectedWink
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Redemption Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 12:41pm
Pt deliberately leaves out the combative medication, azithromycin, that works with it
He is clueless

ALL my posts are written as Sci-Fi, no different to an Orson Welles and should not be taken literally. Sci-fi is a genre of Fiction.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote stayer Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 12:51pm
Thanks for that (whole!) article, Isaac. Interesting stuff. Certainly not a dangerous experiment to use that drug.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 12:56pm
Originally posted by Redemption Redemption wrote:

Pt deliberately leaves out the combative medication, azithromycin, that works with it
He is clueless


Has it been approved for treatment of this disease...anywhere?

Until it is, I am very happy to not recommend people experiment with their lives. 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote max manewer Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 1:10pm
Crackpot "cures" are always quick out of the blocks whenever epidemics arrive. If we can't trust the experts in the field to be better informed about the efficacy of treatments, then better stay away from doctors.
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Originally posted by Redemption Redemption wrote:

Pt deliberately leaves out the combative medication, azithromycin, that works with it
He is clueless


PT doesn't have his precious Rooters to follow, so he has become Head Cheer Leader for the CHINA virus.
In reference to every post in the Trump thread ... "There may have been a tiny bit of license taken there" ... Ok, Thanks for the "heads up" PT!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Passing Through Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 1:36pm
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Shammy Davis Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 2:28pm
Originally posted by Isaac soloman Isaac soloman wrote:

Whole picture pt not just a little bit.
Exactly. Omissions are what PT constantly leans on so that he can claim to be an expert. When PT omits facts, he calculates no one can challenge his posts. If someone does challenge him, he and his hacks just respond with biased information and more omissions.   Don't let him get away with it.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 2:32pm
And that is exactly how the Chinese communist party treats its citizens and the western world.
If that is how you like it max and others 
i feel sorry for you and your naivety.
And in the end is why the world is where it is, at the moment.

Just think, not long ago you were worried that trump was going to push the nuclear button.
CHINA PUSHED SOMETHING WORSE.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 2:33pm
At least the world has a pollution reprieve.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Isaac soloman Quote  Post ReplyReply Direct Link To This Post Posted: 26 Mar 2020 at 2:35pm
When you read that china was making the clothes in Italy and holidaying in Italy bigly
And they are two places to be recovering from pollution
Says something doesnt it.
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